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History of Viagra(Sildenafil Citrate)

admin — Fri, 13 Aug 2010 16:09:29 +0000

Viagra was initially developed to treat heart disease (angina). In trial studies, the penile erection enhancing effects were noticed. The drug was patented in 1996, approved by the FDA on March 27, 1998 (becoming the first pill approved to treat erectile dysfunction in the United States) and offered for sale in the United States later that year. It soon became a smashing success. Even though Viagra is only available by prescription from a doctor, it was advertised directly to consumers on TV (famously being endorsed by Bob Dole). Numerous sites on the Internet offer Viagra for sale after an “online consultation”, a mere web questionnaire. It is likely that many men (and some women) experiment with the drug to increase sexual prowess or pleasure. Annual sales of Viagra in the period 1999 – 2001 exceeded $1 billion.

It has been suggested that Viagra would lead to a marked drop in the demand for certain traditional remedies, such as tiger penises and rhinoceros horns and that the drug may therefore help to preserve these endangered species. However, this is unlikely in that these parts of endangered species are not only used to treat impotence. Rhinoceros horns, for example, are used as a treatment for high fever. Further, since Viagra has not been shown to possess aphrodisiac properties, it is unclear that the natural remedies would compete with this new clinical drug.

The “Viagra” name has become so well known that many fake aphrodisiacs now call themselves “herbal Viagra” or are presented as blue tablets imitating the shape and colour of Pfizer’s product.

Pfizer’s worldwide patents on sildenafil citrate will expire in 2011 – 2013. The UK patent held by Pfizer on the use of PDE5 inhibitors (see below) as treatment of impotence has been invalidated in 2000 because of obviousness; this decision was upheld on appeal in 2002.

A mixture of Viagra and ecstasy, called sextasy, has become popular among rave partygoers.

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Sildenafil Description

admin — Tue, 11 May 2010 18:53:05 +0000

Sildenafil (sil-DEN-a-fil) belongs to a group of medicines that delay the enzymes called phosphodiesterases from working too quickly. The penis is one of the areas where these enzymes work. Sildenafil is used to treat men who have erectile dysfunction (also called sexual impotence).

By controlling the enzyme phosphodiesterase, sildenafil helps to maintain an erection that is produced when the penis is stroked. Without physical action to the penis, such as that occurring during sexual intercourse, sildenafil will not work to cause an erection.

This medicine is available only with your doctor’s prescription, in the following dosage form(s):

Allegra Product Information

admin — Wed, 14 Apr 2010 17:39:09 +0000

Seasonal allergies can make it difficult for you to enjoy what you’re doing. Allegra can help you feel better by relieving allergy symptoms in patients 12 and over, so you can more fully enjoy your world.^TM

Visit our PRODUCT INFORMATION section to learn about:

Once-daily Allegra^® (fexofenadine HCI) 180-mg tablets for seasonal allergic rhinitis in patients 12 and older. NOW AVAILABLE
Allegra^® (fexofenadine HCI) 60-mg tablets & capsules for seasonal allergic rhinitis and chronic idiopathic urticaria hives in patients 12 and older.
Allegra^® (fexofenadine HCI) a pediatric formulation of 30-mg tablets for seasonal allergies and hives for pediatric patients 6-11 years.
Allegra-D^® (fexofenadine HCI 60-mg/pseudoephedrine HCI 120 mg) extended-release tablets for seasonal allergies with nasal congestion in patients 12 and older.

Don’t miss these sections here on our Allegra web site to help you discover the allergy relief you’ve been looking for:

LEARN ABOUT ALLERGIES – find in-depth articles about seasonal allergies, a Glossary of common allergy terminology, Inside Allergies, a cellular animation of what happens in your body during an allergic reaction, and more.
POLLEN FORECAST – Is it an allergy day? Before you go out check for a daily update on pollen counts for your local area.
WHY ALLEGRA? – Claritin^® and Zyrtec^® users will want to check out this section.

Now Allegra^® is Available in 180 mg tablets
Take just one tablet once daily
for 24-hour seasonal allergy relief in patients 12 and older!

Now, Allegra introduces the convenience of long lasting, once-daily seasonal allergy relief with Allegra 180 mg tablets. Imagine the freedom: you take just one Allegra 180 mg tablet once daily for 24-hour seasonal allergy relief!

Allegra is an effective antihistamine that contains fexofenadine—a unique ingredient that combats your seasonal allergy symptoms: itchy, watery eyes. Plus sneezing and runny nose. But unlike some allergy medications, Allegra won’t make you drowsy. In fact, in clinical studies, drowsiness in people who took Allegra 180 mg tablets was similar to placebo (sugar pill), 0.4% vs. 0.0%.

The other formulations of Allegra are also similar to placebo: 60-mg capsules ( 1.3% vs. 0.9%), and 30-mg tablets (0.5% vs. 0.9%).

Claritin, is a registered trademarks of Schering Corporation. Zyrtec is a registered trademark of UCB, Societe Anonyme.

IMPORTANT SAFETY INFORMATION

The most commonly reported adverse events with once-daily Allegra 180-mg tablets and placebo in seasonal allergy patients 12 and older are headache (10.6% vs. 7.5%), upper respiratory tract infection (3.2% vs. 3.1%), and back pain (2.8% vs. 1.4%).

The most commonly reported adverse experiences for Allegra 60-mg capsules and tablets and placebo in seasonal allergy patients 12 and older are cold, flu (2.5% vs. 1.5%), nausea (1.6% vs. 1.5%), and menstrual pain (1.5% vs. 0.3%).

The most commonly reported adverse events with Allegra 30-mg twice daily and placebo in seasonal allergy patients 6-11 years are headache (7.2% vs. 6.6%), upper respiratory tract infection (4.3 % vs. 1.7%), coughing (3.8% vs. 1.3%), and accidental injury (2.9% vs. 1.3%).

Because Allegra-D (fexofenadine HCl 60mg/pseudoephedrine HCl 120mg) extended-release tablets contain pseudoephedrine (the decongestant in most over-the-counter allergy medicines), Allegra-D must not be taken if you are also taking MAO inhibitors (medicines that treat depression) or if you retain urine or have glaucoma, severe high blood pressure, or severe heart disease. Also, let your doctor know before you take Allegra-D if you have high blood pressure, diabetes, heart disease, glaucoma, thyroid disease, impaired kidney function, or symptoms of an enlarged prostate such as difficulty urinating. The most commonly reported adverse experiences with twice-daily Allegra-D extended release tablets compared to pseudoephedrine alone in seasonal allergic rhinitis with nasal congestion in patients 12 and older were headache (13.0% vs. 17.4%), insomnia (12.6% vs. 13.3%), and nausea (7.4% vs. 5.0%).

What is Finasteride?

admin — Tue, 12 Jan 2010 14:46:55 +0000

Finasteride (PROSCAR): U.S. FDA (United States Food and Drug Administration) approved as a prostate gland shrinking medication. Finasteride effectively blocks the enzyme that converts testosterone into a form that enlarges the prostate gland. It is sold as a prescription medication as a 5-milligram tablet under the brand name Proscar.

Merck & Co manufactures Proscar tablets.
Patient Information for Proscar is available in PDF format.

A lower dosage of Finasteride may reduce male baldness.

It was discovered that the same hormone responsible for some prostate gland enlargement plays an important role in signaling certain genetically predisposed hair follicle cells to miniaturize, eventually leading to hair loss.

Finasteride (PROPECIA): U.S. FDA (United States Food and Drug Administration) approved for the treatment of male pattern hair loss on the vertex (top of head) and the anterior mid-scalp area. When prescribed as an anti-baldness medication, Finasteride may be taken orally, or applied topically onto the scalp. The dosage necessary to produce significant hair restoration benefits is much less than the dosage typically prescribed for treating enlarged prostate glands. It is sold as a prescription medication as a 1-milligram tablet under the brand name PROPECIA.

Merck & Co manufactures PROPECIA tablets.

Maximizing success with LEVITRA

admin — Tue, 12 Jan 2010 14:22:54 +0000

Here is a list of tips to help you have a successful experience from the very first try:

LEVITRA should be taken approximately 60 minutes prior to sexual activity. In clinical trials, most patients were able to begin sexual activity before that time.
LEVITRA can be taken with or without food.
If it has been a long time since your partner has had an erection that was hard enough for penetration, don’t give up. Talk to your doctor. LEVITRA may help men with erectile dysfunction (ED) get and keep an erection satisfactory for sexual activity.
Remember to let him know how you feel about him and are ready to explore treatment options together.
Open communication between partners may increase sexual success. The most effective approach is to focus on improving the quality of your sexual life together.
Have fun. Relax. Enjoy.

Erection quality (EQ) and your relationship

admin — Tue, 12 Jan 2010 13:53:22 +0000

When a man notices a change in his erectile function, it can affect his relationship with his partner. Sometimes, one or both partners are reluctant to bring up the subject, which can strain a relationship.

When you know more, you can help get him back on track. Here are some important facts:

A change in erectile function can happen to almost any man. Men sometime notice changes in erectile function as they age. These changes may be temporary, or occasional, or they may progressively become more obvious.